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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1
Acc ID: CHEBI:1156
Term: 2-hydroxyestrone
Definition: A 2-hydroxy steroid that is estrone substituted by a hydroxy group at position 2.
Chemical ID: MESH:C024980
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1affects bindingISORGD:7365596480464CTD2-hydroxyestrone binds to ESR1 protein

PMID:16728493
Esr1multiple interactionsISORGD:7365596480464CTD2-hydroxyestrone binds to and results in increased activity of ESR1 protein

PMID:17713618
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