GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Calca | decreases expression | ISO | Calca (Rattus norvegicus) | 6480464 | CTD | Sumatriptan results in decreased expression of CALCA mRNA | PMID:14715155 | Calca | multiple interactions | ISO | Calca (Rattus norvegicus) | 6480464 | CTD | 3-(3-(dimethylamino)propyl)-4-hydroxy-N-(4-(4-pyridinyl)phenyl)benzamide inhibits the reaction [Sumatriptan results in decreased expression of CALCA mRNA]; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; GR 127935 inhibits the reaction [Sumatriptan results in decreased expression of CALCA mRNA]; isamoltane inhibits the reaction [Sumatriptan results in decreased expression of CALCA mRNA]; Sumatriptan inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; Sumatriptan inhibits the reaction [NGF protein results in increased expression of CALCA mRNA] | PMID:12574409 PMID:14715155 | Calca | multiple interactions | ISO | CALCA (Homo sapiens) | 6480464 | CTD | Sumatriptan results in decreased expression of and results in decreased secretion of CALCA protein | PMID:15689192 | |
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