Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


RGD ID: 736484
Species: Homo sapiens
RGD Object: Gene
Symbol: SQSTM1
Name: sequestosome 1
Acc ID: CHEBI:10447
Term: beta-thujaplicin
Definition: A monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities.
Chemical ID: MESH:C009479
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SQSTM1decreases expressionISORGD:7364856480464CTDbeta-thujaplicin results in decreased expression of SQSTM1 proteinPMID:25044443
Go Back to source page   Continue to Ontology report