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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735440
Species: Homo sapiens
RGD Object: Gene
Symbol: NFKBIA
Name: NFKB inhibitor alpha
Acc ID: CHEBI:102166
Term: thiopental
Definition: A barbiturate, the structure of which is that of 2-thiobarbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Chemical ID: MESH:D013874
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFKBIAdecreases degradationEXP 6480464CTDThiopental results in decreased degradation of NFKBIA proteinPMID:12883408
NFKBIAmultiple interactionsEXP 6480464CTDTNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein]PMID:12883408
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