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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359694
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rap1a
Name: RAP1A, member of RAS oncogene family
Acc ID: CHEBI:101279
Term: GGTI-2133
Definition: An organoammonium salt resulting from the mixing of equimolar amounts of GGTI-2133 free base and trifluoroacetic acid. An inhibitor of geranylgeranyltransferase type I.
Chemical ID: MESH:C547856
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rap1adecreases geranoylationISORAP1A (Homo sapiens)6480464CTDGGTI-2133 results in decreased geranoylation of RAP1A proteinPMID:25578243
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