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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1623761
Species: Mus musculus
RGD Object: Gene
Symbol: Abcc4
Name: ATP-binding cassette, sub-family C member 4
Acc ID: CHEBI:10110
Term: zidovudine
Definition: A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
Chemical ID: MESH:D015215
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc4affects abundanceISOABCC4 (Homo sapiens)6480464CTDABCC4 protein affects the abundance of ZidovudinePMID:18364470
Abcc4increases exportISOABCC4 (Homo sapiens)6480464CTDABCC4 protein results in increased export of ZidovudinePMID:18364470 PMID:18535159
Abcc4increases expressionISOABCC4 (Homo sapiens)6480464CTDZidovudine results in increased expression of ABCC4 mRNAPMID:15456083
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