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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620890
Species: Mus musculus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP-binding cassette, sub-family B member 1A
Acc ID: CHEBI:10110
Term: zidovudine
Definition: A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
Chemical ID: MESH:D015215
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases expressionISOABCB1 (Homo sapiens)6480464CTDZidovudine results in increased expression of ABCB1 mRNA; Zidovudine results in increased expression of ABCB1 proteinPMID:15456083 PMID:18310046 PMID:24292225 PMID:9148857
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