GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IGF1 | decreases expression | EXP | | 6480464 | CTD | Zearalenone results in decreased expression of IGF1 mRNA; Zearalenone results in decreased expression of IGF1 protein | PMID:29758222 | IGF1 | multiple interactions | EXP | | 6480464 | CTD | Zearalenone affects the reaction [IGF1 protein results in increased abundance of Estradiol]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP11A1 mRNA]; Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]; Zearalenone promotes the reaction [IGF1 protein results in increased abundance of Progesterone] | PMID:17656051 | |
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