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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69338
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a6
Name: solute carrier family 22 member 6
Acc ID: CHEBI:10043
Term: wogonin
Definition: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-8.
Chemical ID: MESH:C085514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a6decreases activityISOSLC22A6 (Homo sapiens)6480464CTDwogonin results in decreased activity of SLC22A6 proteinPMID:32159797
Slc22a6multiple interactionsISOSLC22A6 (Homo sapiens)6480464CTD[wogonin results in decreased activity of SLC22A6 protein] which results in increased susceptibility to and results in increased activity of aristolochic acid IPMID:32159797
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