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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734356
Species: Homo sapiens
RGD Object: Gene
Symbol: JUN
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:10037
Term: wedelolactone
Definition: A member of the class of coumestans that is coumestan with hydroxy substituents as positions 1, 8 and 9 and a methoxy substituent at position 3.
Chemical ID: MESH:C051122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JUNmultiple interactionsISOJun (Mus musculus)6480464CTDwedelolactone inhibits the reaction [[Cisplatin co-treated with TNF protein] results in increased phosphorylation of JUN protein]PMID:23103562
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