GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MGP | decreases carboxylation | ISO | Mgp (Rattus norvegicus) | 6480464 | CTD | Warfarin results in decreased carboxylation of MGP protein | PMID:23223575 | MGP | multiple interactions | ISO | Mgp (Mus musculus) | 6480464 | CTD | [[Warfarin co-treated with Vitamin K 1] results in decreased carboxylation of MGP protein] which results in decreased activity of MGP protein; [Warfarin co-treated with Vitamin K 1] results in decreased activity of MGP protein; [Warfarin co-treated with Vitamin K 1] results in decreased carboxylation of MGP protein; [Warfarin co-treated with Vitamin K 1] results in decreased expression of MGP mRNA | PMID:23990204 | MGP | multiple interactions | ISO | Mgp (Rattus norvegicus) | 6480464 | CTD | [Quercetin co-treated with Warfarin] results in decreased carboxylation of MGP protein; [Vitamin K co-treated with Warfarin] results in increased carboxylation of MGP protein; Warfarin inhibits the reaction [Vitamin K 1 results in increased expression of and results in increased secretion of MGP protein modified form]; Warfarin results in decreased expression of and results in decreased secretion of MGP protein; Warfarin results in decreased expression of and results in decreased secretion of MGP protein modified form | PMID:21705322 PMID:23223575 | | ||||||||||||||||||||||
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