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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736615
Species: Homo sapiens
RGD Object: Gene
Symbol: IFNB1
Name: interferon beta 1
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IFNB1increases expressionISOIfnb1 (Mus musculus)6480464CTDdeoxynivalenol results in increased expression of IFNB1 mRNAPMID:14644621 PMID:17090620
IFNB1multiple interactionsISOIfnb1 (Mus musculus)6480464CTDdeoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNB1 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]PMID:14644621 PMID:19857559
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