GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | decreases activity | ISO | PPARG (Homo sapiens) | 6480464 | CTD | deoxynivalenol results in decreased activity of PPARG protein | PMID:27481073 | Pparg | increases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | deoxynivalenol results in increased expression of PPARG mRNA | PMID:18485432 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in increased expression of PPARG protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; lipopolysaccharide, E coli O55-B5 affects the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; PPARG protein affects the reaction [deoxynivalenol results in decreased degradation of CXCL8 mRNA]; U 0126 inhibits the reaction [deoxynivalenol results in increased expression of PPARG mRNA] | PMID:18485432 | |
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