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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14209343
Species: Sus scrofa
RGD Object: Gene
Symbol: IL1A
Name: interleukin 1 alpha
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1Adecreases expressionEXP 6480464CTDdeoxynivalenol results in decreased expression of IL1A mRNA

PMID:23688591
IL1Aincreases expressionEXP 6480464CTDdeoxynivalenol results in increased expression of IL1A mRNA deoxynivalenol results in increased expression of IL1A protein

PMID:23326479 PMID:23688591 PMID:27915442
IL1Amultiple interactionsEXP 6480464CTD[deoxynivalenol co-treated with fumonisin B1] results in decreased expression of IL1A mRNA [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of IL1A mRNA [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA [deoxynivalenol co-treated with nivalenol] results in increased expression of IL1A mRNA [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of IL1A mRNA [deoxynivalenol co-treated with Zearalenone] results in decreased expression of IL1A mRNA [deoxynivalenol co-treated with Zearalenone] results in increased expression of IL1A mRNA deoxynivalenol promotes the reaction [nivalenol results in increased expression of IL1A mRNA] nivalenol promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]

PMID:23688591 PMID:27915442
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