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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14143837
Species: Sus scrofa
RGD Object: Gene
Symbol: MTOR
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MTORdecreases expressionEXP 6480464CTDdeoxynivalenol results in decreased expression of MTOR mRNAPMID:26988607 PMID:32229166
MTORdecreases phosphorylationEXP 6480464CTDdeoxynivalenol results in decreased phosphorylation of MTOR proteinPMID:32229166 PMID:37120089
MTORmultiple interactionsEXP 6480464CTDMelatonin inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein]PMID:37120089
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