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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10787
Species: Mus musculus
RGD Object: Gene
Symbol: Il17a
Name: interleukin 17A
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il17aincreases expressionEXP 6480464CTDdeoxynivalenol results in increased expression of IL17A proteinPMID:32416088
Il17amultiple interactionsEXP 6480464CTD[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL17A protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL17A protein]PMID:28935500 PMID:32416088
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