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GENE - TERM ANNOTATION REPORT

RGD ID: 9057163
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Actn2
Name: actinin alpha 2
Acc ID: DOID:9000727
Term: Syncope
Definition: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
Definition Source(s): MESH:D013575
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Actn2 ISOACTN2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SyncopePMID:23861362 PMID:24033266 PMID:25741868 PMID:26498160 PMID:26899768 PMID:28492532 PMID:30959811
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