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GENE - TERM ANNOTATION REPORT

RGD ID: 9028273
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Sod1
Name: superoxide dismutase 1
Acc ID: DOID:9004009
Term: Reperfusion Injury
Definition: Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Definition Source(s): MESH:D015427
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod1 ISOSod1 (Mus musculus)9068941RGD PMID:15364863 REF_RGD_ID:1580834
Sod1 ISOSOD1 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanism|therapeuticPMID:15364863 PMID:16397181 PMID:23061969 PMID:23743330
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