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GENE - TERM ANNOTATION REPORT

RGD ID: 9026414
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Csf3r
Name: colony stimulating factor 3 receptor
Acc ID: DOID:9119
Term: acute myeloid leukemia
Definition: A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. (DO)
Definition Source(s): http://cancergenome.nih.gov/cancersselected/acutemyeloidleukemia "DO" "DO", http://en.wikipedia.org/wiki/Acute_myeloid_leukemia "DO" "DO", http://www.cancer.gov/dictionary?cdrid=44363 "DO" "DO", https://www.cancer.org/cancer/acute-myeloid-leukemia/detection-diagnosis-staging/how-classified.html "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf3rdisease_progressionISOCSF3R (Homo sapiens)9068941RGD PMID:24746896 REF_RGD_ID:10450468
Csf3rsusceptibilityISOCSF3R (Homo sapiens)9068941RGDassociated with Severe Congenital Neutropenia;DNA:nonsense mutation:cds:PMID:9001427 REF_RGD_ID:10450487
Csf3r ISOCSF3R (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Acute myeloid leukemiaPMID:23604229 PMID:23634996 PMID:23656643 PMID:24081659 PMID:24403076 PMID:24614839 PMID:24854193 PMID:25491280 PMID:25741868 PMID:25932451 PMID:26875968 PMID:27148573 PMID:27581359 PMID:28209919 PMID:28219221 PMID:28492532 PMID:28762112 PMID:30967555 PMID:31697825
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