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GENE - TERM ANNOTATION REPORT

RGD ID: 9018695
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Ager
Name: advanced glycosylation end-product specific receptor
Acc ID: DOID:1287
Term: cardiovascular system disease
Definition: A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Circulatory_system "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ager ISOAger (Rattus norvegicus)9068941RGDassociated with Kidney Failure, Chronic; protein:increased expression:myocardium, aorta (rat)PMID:20056977 REF_RGD_ID:7244145
AgersusceptibilityISOAGER (Homo sapiens)9068941RGDassociated with Diabetes Mellitus, Type 1;DNA:polymorphism:promoter:-374T>A (human)PMID:12606536 REF_RGD_ID:1566451
AgersusceptibilityISOAGER (Homo sapiens)9068941RGDassociated with Diabetic Nephropathies; DNA:deletion, polymorphisms, haplotype:promoter:g.-407_-345del, g.-374T>A, g.-429T>C (human)PMID:20040351 REF_RGD_ID:7244158
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