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GENE - TERM ANNOTATION REPORT

RGD ID: 8998142
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Ptx3
Name: pentraxin 3
Acc ID: DOID:0050073
Term: invasive aspergillosis
Definition: An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage. (DO)
Definition Source(s): http://www.merck.com/mmhe/sec17/ch197/ch197b.html?qt=invasive%20pulmonary%20aspergillosis&alt=sh "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/001326.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptx3 ISOPTX3 (Homo sapiens)9068941RGDprotein:increased expression:bronchoalveolar lavage fluid (human)PMID:28487045 REF_RGD_ID:38508892
Ptx3severityISOPTX3 (Homo sapiens)9068941RGDDNA:SNPs, missense mutation:intron, cds:rs2305619, rs1840680, rs3816527PMID:30275011 REF_RGD_ID:38501097
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