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GENE - TERM ANNOTATION REPORT

RGD ID: 8944041
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Prom1
Name: prominin 1
Acc ID: GO:0071914
Term: prominosome
Definition: An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.
Definition Source(s): GOC:vesicles, PMID:15976444, PMID:17109118, PMID:17283184
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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