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GENE - TERM ANNOTATION REPORT

RGD ID: 8914486
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Serpine1
Name: serpin family E member 1
Acc ID: DOID:552
Term: pneumonia
Definition: A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Pneumonia "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpine1 ISOSERPINE1 (Homo sapiens)9068941RGDPneumonia, Ventilator-Associated; protein:increased expression:Bronchoalveolar Lavage FluidPMID:20473240 REF_RGD_ID:4143511
Serpine1disease_progressionISOSERPINE1 (Homo sapiens)9068941RGDDNA:polymorphism:promoter:PMID:19387177 REF_RGD_ID:4143525
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