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GENE - TERM ANNOTATION REPORT

RGD ID: 8891580
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Agtr1
Name: angiotensin II receptor type 1
Acc ID: PW:0000527
Term: angiotensin II signaling pathway via AT1 receptor
Definition: Angiotensin II signaling through the angiotensin type 1 receptor (AT1) activates downstream signaling pathways and elicits a broad range of physiological responses. It is involved in the regulation of blood pressure and volume, water and electrolyte balance and exerts a potent vasoconstrictive effect.
Definition Source(s): PMID:10977869, PMID:12676164, PMID:16141358
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
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