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GENE - TERM ANNOTATION REPORT

RGD ID: 8885884
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Hmgb1
Name: high mobility group box 1
Acc ID: DOID:9007838
Term: Myocardial Reperfusion Injury
Definition: Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
Definition Source(s): MESH:D015428
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgb1treatmentISOHmgb1 (Rattus norvegicus)9068941RGD PMID:19540007 PMID:23531454 REF_RGD_ID:10402066 REF_RGD_ID:10402170
Hmgb1 ISOHMGB1 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:21113057
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