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GENE - TERM ANNOTATION REPORT

RGD ID: 8795990
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Egfr
Name: epidermal growth factor receptor
Acc ID: PW:0000170
Term: epidermal growth factor/neuregulin signaling pathway
Definition: Members of the EGF/neuregulin superfamily are important regulators of tissue development and repair. A characteristic feature is the presence of the EGF module, a 36-40 amino acid sequence with a disulfide-bonded three-loop structure necessary for receptor binding.
Definition Source(s): GO:0007173, KEGG:map04012, MCW e-journal:J. Mol. Evolo.2000, v50, p397-412, PID:200101, PID:200159, PMID:12814936, Reactome:R-HSA-177929
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egfr ISOEgfr (Rattus norvegicus)9068941RGD PMID:15486316 PMID:16648628 REF_RGD_ID:1581898 REF_RGD_ID:1581908
Egfr ISOEGFR (Homo sapiens)9068941RGD PMID:15982853 REF_RGD_ID:2317963
Egfr ISOEGFR (Homo sapiens)9068941PID PID:200101 PID:200159
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