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GENE - TERM ANNOTATION REPORT

RGD ID: 8795990
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Egfr
Name: epidermal growth factor receptor
Acc ID: GO:0007173
Term: epidermal growth factor receptor signaling pathway
Definition: The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:ceb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egfr ISOEgfr (Rattus norvegicus)9068941RGD PMID:11796513 PMID:15486316 REF_RGD_ID:1581908 REF_RGD_ID:70386
Egfracts_upstream_of_or_withinISOMGI:952909068941MGI MGI:75839 PMID:7641815

MGI:75839 PMID:7641815
Egfracts_upstream_of_or_withinISOEgfr (Mus musculus)9068941MGI MGI:3032880 PMID:14712229 MGI:3531070 PMID:15695332

MGI:3032880 MGI:3531070 PMID:14712229 PMID:15695332
Egfracts_upstream_of_or_withinISOEgfr (Mus musculus)9068941MGI MGI:3766849 PMID:17686994

MGI:3766849 PMID:17686994
Egfracts_upstream_of_or_withinISOEGFR (Homo sapiens)9068941MGI PMID:7736574

PMID:7736574
Egfrinvolved_inISOMGI:1075089068941MGI MGI:5926600 PMID:28783046

MGI:5926600 PMID:28783046
Egfrinvolved_inISOMGI:37635349068941MGI MGI:6342346 PMID:30770250

MGI:6342346 PMID:30770250
Egfrinvolved_inISOEgfr (Mus musculus)9068941MGI MGI:1203410 PMID:9556621 MGI:2136149 PMID:6248866 MGI:2663334 PMID:12761849 MGI:52273 PMID:7678348 MGI:70162 PMID:8456283 MGI:74347 PMID:7752576 MGI:82360 PMID:8702723

MGI:1203410 MGI:2136149 MGI:2663334 MGI:52273 MGI:70162 MGI:74347 MGI:82360 PMID:12761849 PMID:6248866 PMID:7678348 PMID:7752576 PMID:8456283 PMID:8702723 PMID:9556621
Egfrinvolved_inISOEgfr (Mus musculus)9068941MGI MGI:2445853 PMID:12399441 MGI:5468364 PMID:23333074 MGI:5529581 PMID:23899604

MGI:2445853 MGI:5468364 MGI:5529581 PMID:12399441 PMID:23333074 PMID:23899604
Egfrinvolved_inISOEGFR (Homo sapiens)9068941MGI PMID:12435727 PMID:12828935 PMID:9890893

PMID:12435727 PMID:12828935 PMID:9890893
Egfrinvolved_inISOEgfr (Rattus norvegicus)9068941UniProtPMID:20639532

PMID:20639532 REF_RGD_ID:8553583
Egfrinvolved_inISOEGFR (Homo sapiens)9068941UniProt PMID:17655843 PMID:20878056

PMID:17655843 PMID:20878056
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