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GENE - TERM ANNOTATION REPORT

RGD ID: 8768515
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Ripk1
Name: receptor interacting serine/threonine kinase 1
Acc ID: GO:0060545
Term: positive regulation of necroptotic process
Definition: Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
Definition Source(s): GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ripk1 ISORGD:13101589068941RGD PMID:22372834, REF_RGD_ID:7777172
Ripk1 ISORGD:13208969068941UniProtKB (PMID:22028622), (PMID:22274400), (PMID:22817896)

PMID:22028622, PMID:22274400, PMID:22817896
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.