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GENE - TERM ANNOTATION REPORT

RGD ID: 8766282
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: DOID:9007692
Term: Insulin Resistance
Definition: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Definition Source(s): MESH:D007333
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6 ISOIl6 (Rattus norvegicus)9068941RGDassociated with Diabetes Mellitus, Experimental; protein:increased expression:extracellular space (rat)PMID:19328014 REF_RGD_ID:2307252
Il6 ISOIl6 (Rattus norvegicus)9068941RGDmRNA:increased expression:islet of LangerhansPMID:21826222 REF_RGD_ID:10402828
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