Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - TERM ANNOTATION REPORT

RGD ID: 8766282
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: DOID:0080600
Term: COVID-19
Definition: A Coronavirus infectious disease that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2. (DO)
Definition Source(s): https://www.cdc.gov/coronavirus/2019-ncov/about/index.html "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/?term=32007143 "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/?term=32007145 "DO" "DO", https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=2697049 "DO" "DO", https://www.who.int/emergencies/diseases/novel-coronavirus-2019 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6 ISOIL6 (Homo sapiens)9068941RGDprotein:increased expression:plasma (human)PMID:32696007 REF_RGD_ID:38501088
Il6 ISOIL6 (Homo sapiens)9068941RGDprotein:increased expression:serum:PMID:32416070 REF_RGD_ID:30296676
Il6disease_progressionISOIL6 (Homo sapiens)9068941RGD PMID:32407836 REF_RGD_ID:30309206
Il6disease_progressionISOIL6 (Homo sapiens)9068941RGDassociated with diabetes mellitusPMID:32345579 REF_RGD_ID:30296681
Il6severityISOIL6 (Homo sapiens)9068941RGDassociated with cardiovascular system disease;protein:increased expression:blood (human)PMID:32456948 REF_RGD_ID:30309957
Il6severityISOIL6 (Homo sapiens)9068941RGDprotein:increased expression:blood (human)PMID:32181911 REF_RGD_ID:30310230
Il6severityISOIL6 (Homo sapiens)9068941RGDprotein:increased expression:plasma (human)PMID:31986264 REF_RGD_ID:30309212
Il6severityISOIL6 (Homo sapiens)9068941RGDprotein:increased expression:serum (human)PMID:32125452 PMID:32164089 PMID:32227274 PMID:32297828 PMID:32365221 PMID:32427582 PMID:32434211 REF_RGD_ID:27095965 REF_RGD_ID:27226695 REF_RGD_ID:30309200 REF_RGD_ID:30310229 REF_RGD_ID:30310238 REF_RGD_ID:32716368 REF_RGD_ID:36049814
Il6 ISOIL6 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:32026671 PMID:32161940 PMID:32171193 PMID:32534021
Go Back to source page   Continue to Ontology report