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GENE - TERM ANNOTATION REPORT

RGD ID: 8762880
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Actl6a
Name: actin like 6A
Acc ID: PW:0001406
Term: SWI/SNF family mediated chromatin remodeling pathway
Definition: The SWI/SNF (switching defective/sucrose nonfermenting) family of remodelers has initially been purified from Saccharomyces cerevisiae. In mammals, two complexes are comprised of one of two mutually exclusive catalytic ATPase subunits along with a set of conserved core subunits and variant subunits. The SWI/SNF is involved in nucleosome sliding and ejection. Deregulation of pathway is associated with several human cancers.
Definition Source(s): PMID:19355820, PMID:21654818, PMID:23355908
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Actl6a ISOACTL6A (Homo sapiens)9068941RGD PMID:21358755 PMID:23355908 REF_RGD_ID:8694154 REF_RGD_ID:9495920
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