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GENE - TERM ANNOTATION REPORT

RGD ID: 8731185
Species: Chinchilla lanigera
RGD Object: Gene
Symbol: Sftpb
Name: surfactant protein B
Acc ID: DOID:12716
Term: newborn respiratory distress syndrome
Definition: A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts. (DO)
Definition Source(s): http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=respiratory+distress+syndrome "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sftpb ISOSftpb (Rattus norvegicus)9068941RGDmRNA, protein:decreased expression:lungPMID:11504697 REF_RGD_ID:4143428
Sftpb ISOSFTPB (Homo sapiens)9068941RGD PMID:12490037 PMID:18353230 REF_RGD_ID:4143376 REF_RGD_ID:4143416
Sftpb ISOSFTPB (Homo sapiens)9068941RGDDNA:polymorphism:intron (human)PMID:7832777 REF_RGD_ID:4143455
SftpbsusceptibilityISOSFTPB (Homo sapiens)9068941RGDDNA:polymorphism: :p.T131I (human)PMID:11063734 REF_RGD_ID:4143433
SftpbsusceptibilityISOSFTPB (Homo sapiens)9068941RGDDNA:polymorphism:intron (human)PMID:12424586 REF_RGD_ID:4143418
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