GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | decreases expression | EXP | | 6480464 | CTD | lead chloride results in decreased expression of IFNG mRNA | PMID:23503628 | Ifng | multiple interactions | EXP | | 6480464 | CTD | [lead chloride results in increased abundance of Lead] which results in increased expression of IFNG protein; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IFNG protein]; lead chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; lead chloride inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide] | PMID:30836164 PMID:8975779 | Ifng | decreases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | lead chloride results in decreased expression of IFNG protein | PMID:15843504 | |
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