GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | multiple interactions | EXP | | 6480464 | CTD | [arsenic trioxide co-treated with Cyclosporine] affects the expression of IFNG mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; Cyclosporine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Cyclosporine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 protein]; Cyclosporine promotes the reaction [Picryl Chloride results in increased expression of IFNG protein] | PMID:10205001 PMID:15588918 PMID:16442096 PMID:19545743 | Ifng | decreases expression | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | Cyclosporine results in decreased expression of IFNG mRNA | PMID:10454224 | Ifng | decreases secretion | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Cyclosporine results in decreased secretion of IFNG protein | PMID:11692113 | Ifng | multiple interactions | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | [Ciprofloxacin co-treated with Cyclosporine] results in increased expression of IFNG mRNA | PMID:18337667 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Cyclosporine inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IFNG protein]; Cyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA] | PMID:1371491 PMID:15663561 PMID:17475810 PMID:24603311 PMID:29594315 | | ||||||||||||||||||||||
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