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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737488
Species: Mus musculus
RGD Object: Gene
Symbol: Ifng
Name: interferon gamma
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ifngmultiple interactionsEXP 6480464CTD[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of IFNG mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IFNG mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IFNG proteinPMID:30889423 PMID:33148380 PMID:33739591
Ifngaffects expressionISOIFNG (Homo sapiens)6480464CTDArsenic affects the expression of IFNG proteinPMID:20940111
Ifngaffects methylationISOIFNG (Homo sapiens)6480464CTDArsenic affects the methylation of IFNG genePMID:27838757
Ifngdecreases expressionISOIFNG (Homo sapiens)6480464CTDArsenic results in decreased expression of IFNG mRNAPMID:27838757
Ifngmultiple interactionsISOIfng (Rattus norvegicus)6480464CTD[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IFNG protein; mecobalamin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of IFNG protein]PMID:33739591
Ifngmultiple interactionsISOIFNG (Homo sapiens)6480464CTD[Arsenic co-treated with Zidovudine co-treated with IFNG protein] results in increased expression of IL2 mRNA; [Coal results in increased abundance of Arsenic] which results in decreased expression of IFNG mRNAPMID:23962110 PMID:28823652
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