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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737487
Species: Homo sapiens
RGD Object: Gene
Symbol: IFNG
Name: interferon gamma
Acc ID: CHEBI:52290
Term: mitogen
Definition: A chemical substance that encourages a cell to commence cell division, triggering mitosis.
Chemical ID: MESH:D008934
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IFNGincreases expressionISOIfng (Rattus norvegicus)6480464CTDMitogens results in increased expression of IFNG proteinPMID:19401694
IFNGincreases expressionISOIfng (Mus musculus)6480464CTDMitogens results in increased expression of IFNG proteinPMID:30664314
IFNGincreases secretionISOIfng (Mus musculus)6480464CTDMitogens results in increased secretion of IFNG proteinPMID:30536526
IFNGmultiple interactionsISOIfng (Rattus norvegicus)6480464CTDCiprofloxacin inhibits the reaction [irinotecan promotes the reaction [Mitogens results in increased expression of IFNG protein]]; irinotecan inhibits the reaction [Mitogens results in increased expression of IFNG protein]; irinotecan promotes the reaction [Mitogens results in increased expression of IFNG protein]PMID:19401694
IFNGmultiple interactionsISOIfng (Mus musculus)6480464CTDfluorotelomer alcohols inhibits the reaction [Mitogens results in increased secretion of IFNG protein]PMID:30536526
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