GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | multiple interactions | EXP | | 6480464 | CTD | [Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein; cyclopamine inhibits the reaction [polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; cyclopamine promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]; polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein] | PMID:27481074 | Cat | decreases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Glucose results in decreased activity of CAT protein | PMID:23192364 PMID:26054749 | Cat | decreases activity | ISO | CAT (Homo sapiens) | 6480464 | CTD | Glucose results in decreased activity of CAT protein | PMID:28911973 PMID:37586544 | Cat | decreases expression | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Glucose results in decreased expression of CAT mRNA | PMID:21818840 | Cat | increases activity | ISO | CAT (Homo sapiens) | 6480464 | CTD | Glucose results in increased activity of CAT protein | PMID:32602595 | Cat | increases expression | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of CAT protein | PMID:28027979 | Cat | increases expression | ISO | CAT (Homo sapiens) | 6480464 | CTD | Glucose deficiency results in increased expression of CAT protein; Glucose results in increased expression of CAT protein | PMID:23494737 | Cat | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in decreased activity of CAT protein; CAT protein inhibits the reaction [Glucose results in increased expression of AGT mRNA]; CAT protein inhibits the reaction [Glucose results in increased expression of AGT protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Glucose results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Glucose results in increased expression of PLCB2 protein]; naringenin inhibits the reaction [Glucose results in decreased activity of CAT protein]; resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in decreased activity of CAT protein]; resveratrol inhibits the reaction [Glucose results in decreased activity of CAT protein] | PMID:12130563 PMID:20691780 PMID:23192364 PMID:23421680 PMID:26054749 | Cat | multiple interactions | ISO | CAT (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; [Glucose deficiency co-treated with CAT] affects the localization of ENDOG protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP9 protein; [Glucose deficiency co-treated with CAT] results in increased cleavage of PARP1 protein; CAT inhibits the reaction [Glucose deficiency affects the folding of SOD2 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]; CAT inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]; CAT protein inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; cyclopamine inhibits the reaction [SHH protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; Furans analog inhibits the reaction [Glucose results in decreased activity of CAT protein]; SHH protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of CAT protein]; solanesol inhibits the reaction [Glucose results in decreased activity of CAT protein]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] | PMID:17309078 PMID:20691780 PMID:23494737 PMID:27481074 PMID:28911973 PMID:32602595 PMID:37586544 | | ||||||||||||||||||||||
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