GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | decreases activity | EXP | | 6480464 | CTD | chromium hexavalent ion results in decreased activity of CAT protein | PMID:16979809 | Cat | decreases expression | EXP | | 6480464 | CTD | chromium hexavalent ion results in decreased expression of CAT protein | PMID:22552367 | Cat | increases activity | EXP | | 6480464 | CTD | chromium hexavalent ion results in increased activity of CAT protein | PMID:11337112 | Cat | multiple interactions | EXP | | 6480464 | CTD | [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased activity of CAT protein | PMID:31756458 | Cat | affects activity | ISO | CAT (Homo sapiens) | 6480464 | CTD | CAT protein affects the activity of chromium hexavalent ion | PMID:11678602 | Cat | decreases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | chromium hexavalent ion results in decreased activity of CAT protein | PMID:17822687 PMID:19913299 PMID:20079796 PMID:21543464 PMID:22344852 PMID:22972417 PMID:32679048 PMID:36108929 | Cat | decreases expression | ISO | CAT (Homo sapiens) | 6480464 | CTD | chromium hexavalent ion results in decreased expression of CAT mRNA | PMID:29069462 | Cat | decreases response to substance | ISO | CAT (Homo sapiens) | 6480464 | CTD | CAT protein results in decreased susceptibility to chromium hexavalent ion | PMID:10574974 PMID:10946250 PMID:21742780 | Cat | increases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | chromium hexavalent ion results in increased activity of CAT protein | PMID:20494564 | Cat | increases expression | ISO | CAT (Homo sapiens) | 6480464 | CTD | chromium hexavalent ion results in increased expression of CAT protein | PMID:20186739 | Cat | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased activity of CAT protein; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; S-allylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased activity of CAT protein]; Selenium inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Selenium inhibits the reaction [chromium hexavalent ion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein] | PMID:17822687 PMID:19913299 PMID:20079796 PMID:20494564 PMID:22344852 PMID:22972417 PMID:28988497 PMID:36108929 | Cat | multiple interactions | ISO | CAT (Homo sapiens) | 6480464 | CTD | CAT protein inhibits the reaction [chromium hexavalent ion results in decreased expression of CDH1 protein]; CAT protein inhibits the reaction [chromium hexavalent ion results in decreased expression of PDCD4 mRNA]; CAT protein inhibits the reaction [chromium hexavalent ion results in decreased expression of PDCD4 protein]; CAT protein inhibits the reaction [chromium hexavalent ion results in increased activity of FYN protein]; CAT protein inhibits the reaction [chromium hexavalent ion results in increased chemical synthesis of Hydroxyl Radical]; CAT protein inhibits the reaction [chromium hexavalent ion results in increased expression of and results in increased activity of CTNNB1 protein]; CAT protein inhibits the reaction [chromium hexavalent ion results in increased expression of MIR21 mRNA]; CAT protein inhibits the reaction [chromium hexavalent ion results in increased expression of VIM protein]; chromium hexavalent ion results in decreased expression of and results in decreased activity of CAT protein | PMID:11678602 PMID:12902192 PMID:22552367 PMID:23518002 PMID:27323401 PMID:27344173 PMID:29069462 | | ||||||||||||||||||||||
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