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GENE - TERM ANNOTATION REPORT

RGD ID: 737444
Species: Mus musculus
RGD Object: Gene
Symbol: Gabrg1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
Acc ID: GO:0007165
Term: signal transduction
Definition: The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
Definition Source(s): GOC:go_curators, GOC:mtg_signaling_feb11
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
 IBAPANTHER:PTN000434994, UniProtKB:P11230, UniProtKB:P17787, UniProtKB:P30926, UniProtKB:P32297, UniProtKB:P36544, UniProtKB:P43681, UniProtKB:Q158222290270GO_Central (PMID:21873635)

PMID:21873635
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.