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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737431
Species: Mus musculus
RGD Object: Gene
Symbol: Gsto1
Name: glutathione S-transferase omega 1
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsto1increases expressionISOGsto1 (Rattus norvegicus)6480464CTDlead acetate results in increased expression of GSTO1 mRNAPMID:11578147
Gsto1multiple interactionsISOGSTO1 (Homo sapiens)6480464CTD[lead acetate results in increased abundance of Lead] which results in decreased expression of GSTO1 mRNA; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GSTO1 mRNA]; Rosmarinic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GSTO1 mRNA]PMID:31610155
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