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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737414
Species: Mus musculus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh1increases expressionEXP 6480464CTDOxygen deficiency results in increased expression of CDH1 mRNAPMID:24205000
Cdh1multiple interactionsEXP 6480464CTD[Butylated Hydroxytoluene co-treated with Oxygen] results in decreased expression of CDH1 proteinPMID:16272459
Cdh1decreases expressionISOCDH1 (Homo sapiens)6480464CTDOxygen deficiency results in decreased expression of CDH1 mRNA; Oxygen deficiency results in decreased expression of CDH1 proteinPMID:22340517 PMID:25351418
Cdh1multiple interactionsISOCDH1 (Homo sapiens)6480464CTD[dictamnine co-treated with Oxygen deficiency] results in increased expression of CDH1 protein; [Oxygen deficiency co-treated with Oxygen] results in increased expression of CDH1 protein; ALCAM protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of CDH1 protein]; ALKBH5 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of CDH1 protein]; DICER1 protein inhibits the reaction [Oxygen deficiency results in decreased expression of CDH1 mRNA]; HIF1A protein promotes the reaction [Oxygen deficiency results in decreased expression of CDH1 mRNA]; PKF115-584 promotes the reaction [ALKBH5 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of CDH1 protein]]; PPARG protein inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of CDH1 protein]PMID:22340517 PMID:25351418 PMID:30266538 PMID:34995009
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