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GENE - TERM ANNOTATION REPORT

RGD ID: 737384
Species: Mus musculus
RGD Object: Gene
Symbol: Chrng
Name: cholinergic receptor, nicotinic, gamma polypeptide
Acc ID: GO:0045202
Term: synapse
Definition: The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
Definition Source(s): GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrngis_active_inIBAPANTHER:PTN000434994 or MGI:95625 or WB:WBGene00001373 or MGI:95613 or Gabrg2 (Rattus norvegicus) or UniProtKB:P47869 or MGI:95748 or Chrna3 (Rattus norvegicus) or MGI:87895 or Chrna9 (Rattus norvegicus) or UniProtKB:P13536 or MGI:95618 or MGI:3609260 or UniProtKB:Q866A2 or MGI:95751 or Gabrr2 (Rattus norvegicus) or Gabra2 (Rattus norvegicus) or UniProtKB:Q04844 or MGI:87888 or Chrna10 (Rattus norvegicus) or Gabra1 (Rattus norvegicus) or MGI:95621 or WB:WBGene00002974 or Gabra4 (Rattus norvegicus) or Gabrb1 (Rattus norvegicus) or Chrna7 (Rattus norvegicus) or MGI:99779 or MGI:95614 or Glra1 (Rattus norvegicus) or UniProtKB:G5EDF1 or Chrna6 (Rattus norvegicus) or UniProtKB:P02708 or MGI:87891 or Gabra3 (Rattus norvegicus) or Htr3a (Rattus norvegicus) or WB:WBGene00006797 or MGI:95619 or MGI:95622 or MGI:106213 or MGI:87885 or WB:WBGene00013746 or FB:FBgn0086778 or WB:WBGene00006784 or MGI:95624 or UniProtKB:P02715 or MGI:95620 or Gabrd (Rattus norvegicus) or Chrna4 (Rattus norvegicus) or Glra3 (Rattus norvegicus) or WB:WBGene00006765 or WB:WBGene00001133 or MGI:87892 or UniProtKB:Q07001 or MGI:106212 or FB:FBgn0000038 or MGI:87894 or MGI:87890 or Gabra5 (Rattus norvegicus) or MGI:95747 or MGI:95749 or ZFIN:ZDB-GENE-040808-32 or Gabre (Rattus norvegicus) or MGI:103156 or Chrnb2 (Rattus norvegicus) or MGI:87893 or Gabra6 (Rattus norvegicus) or WB:WBGene00006774 or Gabrb2 (Rattus norvegicus) or UniProtKB:P11230 or ZFIN:ZDB-GENE-070821-4 or Glrb (Rattus norvegicus) or MGI:95623 or Gabrb3 (Rattus norvegicus) or MGI:95750 or MGI:87887 or MGI:95615 or MGI:87889 or ZFIN:ZDB-GENE-030131-38052290270GO_Central GO_REF:0000033
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