GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PKLR | decreases expression | ISO | Pklr (Rattus norvegicus) | 6480464 | CTD | Streptozocin results in decreased expression of PKLR mRNA | PMID:20363216 | PKLR | multiple interactions | ISO | Pklr (Mus musculus) | 6480464 | CTD | [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA] | PMID:25446853 PMID:26522834 | PKLR | multiple interactions | ISO | Pklr (Rattus norvegicus) | 6480464 | CTD | cinnamaldehyde inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA] | PMID:20363216 | | ||||||||||||||||||||||
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