GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pde5a | increases expression | ISO | Pde5a (Rattus norvegicus) | 6480464 | CTD | Copper results in increased expression of PDE5A mRNA | PMID:30556269 | Pde5a | multiple interactions | ISO | PDE5A (Homo sapiens) | 6480464 | CTD | [Disulfiram binds to Copper] which results in increased expression of PDE5A mRNA; [NSC 689534 binds to Copper] which results in increased expression of PDE5A mRNA; [Thiosemicarbazones binds to Copper] which results in increased expression of PDE5A protein | PMID:20931265 PMID:20971185 PMID:24690739 | |
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