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GENE - TERM ANNOTATION REPORT

RGD ID: 737336
Species: Homo sapiens
RGD Object: Gene
Symbol: GRIA3
Name: glutamate ionotropic receptor AMPA type subunit 3
Acc ID: GO:0035249
Term: synaptic transmission, glutamatergic
Definition: The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Definition Source(s): GOC:dos
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRIA3involved_inIBAFB:FBgn0004620 or FB:FBgn0020429 or FB:FBgn0039916 or MGI:95813 or MGI:95814 or MGI:95815 or MGI:95818 or PANTHER:PTN001826301 or Grin2d (Rattus norvegicus) or WB:WBGene00001612150520179GO_Central GO_REF:0000033
GRIA3involved_inIEAPANTHER:PTHR18966:SF151150520179TreeGrafter GO_REF:0000118
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