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GENE - TERM ANNOTATION REPORT

RGD ID: 737312
Species: Homo sapiens
RGD Object: Gene
Symbol: AGER
Name: advanced glycosylation end-product specific receptor
Acc ID: DOID:784
Term: chronic kidney disease
Definition: A kidney failure that is characterized by the gradual loss of kidney function. (DO)
Definition Source(s): https://www.mayoclinic.org/diseases-conditions/chronic-kidney-disease/symptoms-causes/syc-20354521 "DO" "DO", https://www.ncbi.nlm.nih.gov/books/NBK499861/ "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AGERdisease_progressionIAGP 7243185RGDDNA:polymorphism:promoter:g.-374T>A (human) 
AGERseverityIAGP 7242570RGDDNA:polymorphisms:promoter, intron:g.-429T>C, g.2184A>G (human) 
AGERsusceptibilityIAGP 7244142RGDassociated with Diabetes Mellitus, Type 2; DNA:polymorphism:promoter:g.-429T>C (human) 
AGER IDA 7243958RGD  
AGER IEP 7243867RGDprotein:increased expression:serum (human) 
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