GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AGER | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of AGER mRNA; Glucose results in increased expression of AGER protein | PMID:19557821 PMID:19833897 | AGER | multiple interactions | EXP | | 6480464 | CTD | GLO1 inhibits the reaction [Glucose promotes the reaction [RELA protein binds to AGER promoter]]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER protein]; Glucose promotes the reaction [RELA protein binds to AGER promoter]; Luteolin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; RELA promotes the reaction [Glucose results in increased expression of AGER mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; SOD2 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; SOD2 inhibits the reaction [Glucose results in increased expression of AGER protein]; UCP1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; UCP1 inhibits the reaction [Glucose results in increased expression of AGER protein] | PMID:19557821 PMID:19833897 | AGER | increases expression | ISO | Ager (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of AGER protein | PMID:19759273 | AGER | multiple interactions | ISO | Ager (Rattus norvegicus) | 6480464 | CTD | AGER protein results in increased susceptibility to [Azoxymethane co-treated with Glucose co-treated with Linoleic Acid]; Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]; Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Losartan inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Losartan inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]] | PMID:22467055 | AGER | multiple interactions | ISO | Ager (Mus musculus) | 6480464 | CTD | [Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]] | PMID:30101366 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |