GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PRNP | affects binding | EXP | | 6480464 | CTD | PRNP protein binds to Copper Sulfate; PRNP protein polymorphism binds to Copper Sulfate | PMID:16847141 | PRNP | increases expression | EXP | | 6480464 | CTD | Copper Sulfate results in increased expression of PRNP mRNA | PMID:19549813 | PRNP | multiple interactions | EXP | | 6480464 | CTD | Copper Sulfate results in increased uptake of and affects the localization of PRNP protein; Filipin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein]; Nystatin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] | PMID:11994310 | PRNP | affects binding | ISO | Prnp (Mus musculus) | 6480464 | CTD | PRNP protein binds to Copper Sulfate | PMID:16787422 | PRNP | decreases response to substance | ISO | Prnp (Mus musculus) | 6480464 | CTD | PRNP protein results in decreased susceptibility to Copper Sulfate | PMID:16787422 | PRNP | multiple interactions | ISO | Prnp (Mus musculus) | 6480464 | CTD | Copper Sulfate results in increased uptake of and affects the localization of PRNP protein; Filipin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein]; Nystatin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] | PMID:11994310 | | ||||||||||||||||||||||
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