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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737278
Species: Mus musculus
RGD Object: Gene
Symbol: Slc22a1
Name: solute carrier family 22 (organic cation transporter), member 1
Acc ID: CHEBI:34328
Term: 3-Amino-1-methyl-5H-pyrido[4,3-b]indole
Definition: A pyridoindole that has formula C12H11N3.
Chemical ID: MESH:C019133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a1decreases activityISOSLC22A1 (Homo sapiens)6480464CTD3-amino-1-methyl-5H-pyrido(4,3-b)indole results in decreased activity of SLC22A1 proteinPMID:30189235
Slc22a1multiple interactionsISOSLC22A1 (Homo sapiens)6480464CTD3-amino-1-methyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A1 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]; 3-amino-1-methyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A1 protein results in increased import of Tetraethylammonium]PMID:30189235
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