GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SLC2A1 | affects expression | EXP | | 6480464 | CTD | Oxygen deficiency affects the expression of SLC2A1 protein | PMID:34900531 | SLC2A1 | decreases response to substance | EXP | | 6480464 | CTD | SLC2A1 protein results in decreased susceptibility to Oxygen deficiency | PMID:10780954 | SLC2A1 | increases expression | EXP | | 6480464 | CTD | Oxygen deficiency results in increased expression of SLC2A1 mRNA; Oxygen deficiency results in increased expression of SLC2A1 protein | PMID:10780954 PMID:12032628 PMID:15525582 PMID:15741220 PMID:16025159 PMID:17442736 PMID:19695866 PMID:19808899 PMID:20042640 PMID:20423107 PMID:22279137 PMID:23424623 PMID:23466666 PMID:24236059 PMID:24292262 PMID:25469848 PMID:25596134 PMID:26282490 PMID:26516004 PMID:29475939 PMID:29630948 PMID:29690507 PMID:7493931 | SLC2A1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]; 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; [Cisplatin co-treated with eprenetapopt] promotes the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; [cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of SLC2A1 protein; [Deferoxamine results in decreased abundance of Oxygen] which results in increased expression of SLC2A1 protein; annonacin inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; bruceine D affects the reaction [Oxygen deficiency affects the expression of SLC2A1 protein]; CTNNBIP1 protein affects the reaction [bruceine D affects the reaction [Oxygen deficiency affects the expression of SLC2A1 protein]]; dihydrotanshinone I inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]; eprenetapopt promotes the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; genipin inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]; Minocycline inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; Oxygen deficiency inhibits the reaction [Cisplatin results in decreased expression of SLC2A1 mRNA]; Polyphenols inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; Propolis inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; PTEN protein inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]]; PTEN protein inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]]; Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; SLC2A1 protein inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]; ST6GAL1 protein promotes the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA] | PMID:10780954 PMID:17442736 PMID:19091749 PMID:19808899 PMID:20423107 PMID:22279137 PMID:24292262 PMID:26282490 PMID:29475939 PMID:29630948 PMID:29690507 PMID:34900531 | SLC2A1 | decreases expression | ISO | Slc2a1 (Mus musculus) | 6480464 | CTD | Oxygen results in decreased expression of SLC2A1 mRNA | PMID:23034257 | SLC2A1 | increases expression | ISO | Slc2a1 (Mus musculus) | 6480464 | CTD | Oxygen deficiency results in increased expression of SLC2A1 mRNA | PMID:20412331 PMID:20880076 PMID:23437309 PMID:23539316 PMID:24639359 | SLC2A1 | increases expression | ISO | Slc2a1 (Rattus norvegicus) | 6480464 | CTD | Oxygen deficiency results in increased expression of SLC2A1 mRNA; Oxygen deficiency results in increased expression of SLC2A1 protein | PMID:11524615 PMID:15525582 PMID:18331222 PMID:19278353 PMID:23307114 PMID:25469848 | SLC2A1 | multiple interactions | ISO | Slc2a1 (Mus musculus) | 6480464 | CTD | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SLC2A1 mRNA; ARNT gene mutant form inhibits the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA] | PMID:20412331 PMID:24639359 PMID:30529165 | SLC2A1 | multiple interactions | ISO | Slc2a1 (Rattus norvegicus) | 6480464 | CTD | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of SLC2A1 mRNA; [Oxygen deficiency co-treated with cobaltous chloride] results in increased expression of SLC2A1 mRNA; [Oxygen deficiency co-treated with cobaltous chloride] results in increased expression of SLC2A1 protein; Progesterone promotes the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]; Trimetazidine promotes the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA] | PMID:18331222 PMID:19278353 PMID:23307114 PMID:25937560 PMID:33729688 | | ||||||||||||||||||||||
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